Commune with Jeff Krasno
Is This Right for Me? NAD+: Why the "Longevity Molecule" Story Just Got Complicated
· 51 min
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About this episode
NAD+ has become the longevity industry's favorite molecule, sold as as a supplement and as a four-hour IV that promises sharper thinking, more energy, and slower aging. But a new 2026 paper complicates the very story it was built on.
In this episode, Jeff breaks down what NAD+ actually is, what the human trials really show, and why the gap between a $40 oral supplement and a $1,200 IV drip matters more than the marketing admits.
You’ll learn about:
- What NAD+ does in the body and why it got tied to aging
- The new research questioning whether NAD+ truly declines with age
- Oral NR and NMN versus IV infusions, and what the evidence supports
- The risks rarely mentioned, including the cancer question
- Why the saline, B vitamins, and forced rest may explain how good people feel
This episode is for anyone weighing NAD+, longevity supplements, or an IV drip, and who wants to tell real science from wellness hype first.
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About Commune with Jeff Krasno
The Commune Podcast is where we explore the ideas and practices that help us live healthy, connected, purpose-filled lives.
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