Commune with Jeff Krasno : Is This Right for Me? NAD+: Why the "Longevity Molecule" Story Just Got Complicated

SHOW NOTES

NAD+ has become the longevity industry's favorite molecule, sold as as a supplement and as a four-hour IV that promises sharper thinking, more energy, and slower aging. But a new 2026 paper complicates the very story it was built on. In this episode, Jeff breaks down what NAD+ actually is, what the human trials really show, and why the gap between a $40 oral supplement and a $1,200 IV drip matters more than the marketing admits. You’ll learn about: What NAD+ does in the body and why it got tied to aging The new research questioning whether NAD+ truly declines with age Oral NR and NMN versus IV infusions, and what the evidence supports The risks rarely mentioned, including the cancer question Why the saline, B vitamins, and forced rest may explain how good people feel This episode is for anyone weighing NAD+, longevity supplements, or an IV drip, and who wants to tell real science from wellness hype first. This episode was made possible by: LMNT: Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at drinklmnt.com/commune. Stemregen: Get 20% off your first order at stemregen.co/commune with the code COMMUNEPOD Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 15% off your order at ⁠vivobarefoot.com/commune⁠. Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off our entire product line. Sunlighten: Visit sunlighten.com/commune Up to 2,100 off saunas and $50 off Red Light Products with code “COMMUNE”
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Commune with Jeff Krasno
Commune is a podcast where we explore the ideas and practices that bring us together and help us live healthy, purpose-filled lives. We believe personal and societal health are two sides of the same coin, and that cultivating personal wellness is the first step toward making the world well. We connect with experts, scientists, and storytellers around food, health, social impact, mindfulness and movement practices, personal growth, and environmental action. In addition to being a podcast, Commune is also an online course platform where thousands of participants take each course together, day-by-day, for free. We then provide social tools that empower participants to form local action groups and implement their new knowledge in their communities.

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