Commune with Jeff Krasno
The Menopause Gut: How Hormones Shape Your Microbiome with Cynthia Thurlow
June 4, 2026 · 1 hr 7 min
Why listen
Find out how declining estrogen reshapes your gut, drives inflammation, and what you can do about it.
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In this episode
- How estrogen loss changes the gut microbiome and raises inflammation
- What the estrobolome is and why it matters for hormone balance
- Why women bear the majority of autoimmune disease diagnoses
- Practical nutrition and lifestyle steps for midlife gut health
About this episode
What happens to your gut when estrogen declines?
In this episode, Jeff sits down with Cynthia Thurlow, nurse practitioner and author of The Menopause Gut, to explore the overlooked connection between hormones and digestive health.
- How declining estradiol impacts the microbiome and increases inflammation
- What is the estrobolome and estrogen processing in the gut
- Why 80% of autoimmune conditions affect women
- Sleep, stress, and their cascading effects on gut health
- Practical protocols for nutrition, movement, and hormone optimization
This episode is for women navigating perimenopause and menopause, anyone curious about the gut-hormone connection, and those seeking science-backed strategies for midlife health.
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About Commune with Jeff Krasno
The Commune Podcast is where we explore the ideas and practices that help us live healthy, connected, purpose-filled lives.
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