How to Use Psychedelics to Face Death with Clarity | Christine Caldwell
December 9, 2025 · 38 min
Why listen
A psychedelic care educator explains how psilocybin, ketamine, and MDMA can ease fear at the end of life.
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In this episode
- What psychedelic-assisted end-of-life care actually involves in practice
- How specific medicines may reduce anxiety, depression, and fear of dying
- Real patient stories involving cancer, ALS, chronic pain, and major diagnoses
- Practical first steps for yourself, a loved one, or a client
About this episode
Facing death doesn’t just raise medical questions—it opens up deep emotional, spiritual, and existential ones, too.In this episode of the Digital Legacy Podcast, host Niki Weiss, Digital Thanatologist, sits down with Christine Caldwell, an end-of-life psychedelic care educator and the Founder of End of Life Psychedelic Care, to explore how psychedelic-assisted experiences can support people living with terminal or life-threatening illnesses. Together, they discuss how medicines like psilocybin, ketamine, and MDMA can ease fear, reduce existential distress, deepen connection, and help people make meaning—often when time feels short.You’ll discover:What psychedelic-assisted care looks like in an end-of-life context (and what it isn’t)How psilocybin, ketamine, and MDMA may help reduce anxiety, depression, and fear of dyingPowerful real-life stories of patients facing cancer, ALS, chronic pain, and major diagnosesWhy psychedelics can support forgiveness, emotional resolution, and a deeper sense of peacePractical first steps if you’re curious about this work—for yourself, a loved one, or your clients
If you’re interested in digital legacy, end-of-life planning, grief support, or new ways to bring more meaning and calm into the dying process, this conversation offers a grounded, compassionate look at a rapidly emerging area of care.

About Death and Dying in the Digital Age
They say we die twice: once when we take our last breath and again when our name is spoken for the final time. But in today's world, there's a third passing to consider - our digital death. Welcome to Death and Dying in the Digital Age, a podcast that explores the uncharted territory of our online afterlife.
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